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Updated: May 13, 2026

Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue
12:40

Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue

Published on: June 6, 2016

Placenta membranacea.

Samadh F Ravangard, Kimberly Henderson, Kisti Fuller

    Archives of Gynecology and Obstetrics
    |March 8, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Placenta membranacea is a rare placental disorder where chorionic villi cover fetal membranes. This condition can cause significant vaginal bleeding during pregnancy, necessitating careful diagnosis and management.

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    Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue
    12:40

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    Published on: June 6, 2016

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    Ex Vivo Placental Explant Flow Culture - Mimicking the Dynamic Conditions In Utero

    Published on: September 8, 2023

    Area of Science:

    • Reproductive Medicine
    • Obstetrics
    • Pathology

    Background:

    • Placenta membranacea is a rare placental anomaly.
    • It involves fetal membranes being covered by chorionic villi, either partially or completely.
    • This condition can lead to significant obstetric complications.

    Observation:

    • A case of partial placenta membranacea is presented in a 35-year-old primigravida woman.
    • The patient presented with preterm labor at 24 weeks and 5 days gestation.
    • She developed heavy vaginal bleeding, leading to a classical cesarean delivery for suspected abruption.

    Findings:

    • Postpartum placental examination revealed a small placenta with tan membranes and scattered cotyledons.
    • Histologic examination confirmed chorionic villi attached to the fetal membranes, consistent with partial placenta membranacea.
    • The case highlights the diagnostic features of this rare placental disorder.

    Implications:

    • Placenta membranacea should be considered in the differential diagnosis of painless vaginal bleeding in the second and third trimesters.
    • This condition is associated with increased risks of other placental abnormalities like placenta previa and accreta.
    • Adverse perinatal outcomes, including stillbirth, preterm delivery, and neonatal death, are potential complications.