Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-patch Base Excision Repair

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pseudotumoral multiple sclerosis: unveiling its clinical and imaging characteristics.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026

Same author

Postoperative spinal arachnoid cysts: a reversible cause of acute myelopathy.

Practical neurology·2026

Same author

Episodic cerebellar ataxia mimicking stroke - diagnostic and therapeutic lessons from SCA27B.

Parkinsonism & related disorders·2026

Same author

Early postoperative quality of life in glioma patients - A prospective cohort study.

Neurocirugia·2025

Same author

Burst of microembolic signals during carotid ultrasound unveils serious plaque instability.

Practical neurology·2025

Same author

Measuring Rigidity During Deep Brain Stimulation Surgery: Evidence of Clinical Benefits in Patients With Advanced Idiopathic Parkinson's Disease.

Cureus·2025

Search research articles

Related Experiment Video

Updated: May 13, 2026

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

One-step tunneling of DBS extensions--a technical note.

Paulo Linhares¹, Bruno Carvalho, Rui Vaz

¹Department of Neurosurgery, Centro Hospitalar de São João, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.

Acta Neurochirurgica

|March 8, 2013

Summary

A novel one-step tunneling technique for deep brain stimulation (DBS) extensions significantly reduces retroauricular wound complications and infections in Parkinson's disease patients.

More Related Videos

Detection and Quantification of Tunneling Nanotubes Using 3D Volume View Images

Detection and Quantification of Tunneling Nanotubes Using 3D Volume View Images

Published on: August 31, 2022

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

Published on: June 26, 2015

Related Experiment Videos

Last Updated: May 13, 2026

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Detection and Quantification of Tunneling Nanotubes Using 3D Volume View Images

Detection and Quantification of Tunneling Nanotubes Using 3D Volume View Images

Published on: August 31, 2022

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

Published on: June 26, 2015

Area of Science:

Neurosurgery
Medical Engineering

Background:

Infections are a major complication in deep brain stimulation (DBS) surgery, potentially leading to device removal.
Retroauricular incision sites are particularly vulnerable to skin erosion and wound dehiscence.
Current prevention strategies include complex reconstruction techniques and extended antibiotic treatments.

Purpose of the Study:

To introduce and evaluate a simplified surgical technique for tunneling DBS extensions.
To prevent wound complications and reduce infection rates associated with DBS surgery.

Main Methods:

A one-step tunneling technique for DBS extensions was employed in 20 patients undergoing subthalamic DBS for Parkinson's disease.
This technique specifically avoids opening the retroauricular space during the tunneling procedure.

Main Results:

No instances of retroauricular skin erosion were observed following the implantation using the described technique.
A reduction in the incidence of infections was noted in patients who underwent this procedure.

Conclusions:

The described surgical approach offers a straightforward method to minimize wound and erosion complications.
This technique provides significant benefits for patients undergoing deep brain stimulation surgery.