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Published on: August 22, 2012
Strongyloidiasis: an emerging infectious disease in China
Chunmei Wang1, Jiabao Xu, Xiaohong Zhou
1Key Laboratory of Prevention and Control for Emerging Infectious Diseases of Guangdong Higher Institutes, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, Guangdong, China. wangcmq@163.com
The American Journal of Tropical Medicine and Hygiene
|March 8, 2013
Summary
Strongyloidiasis is an emerging parasitic infection in China, particularly affecting immunocompromised individuals. Increased clinical awareness and early diagnosis are crucial for managing this disease and improving patient outcomes.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Epidemiology
Background:
- Strongyloidiasis, a parasitic infection, has seen a rise in reported cases in China since 1973.
- A significant proportion of cases (63%) occurred in the decade preceding the study.
- Immunocompromised individuals and those on cortical hormone therapy represent a high-risk group (68% of cases).
Purpose of the Study:
- To conduct a meta-analysis of strongyloidiasis cases in China.
- To analyze clinical symptoms, diagnostic methods, and outcomes.
- To highlight the emerging nature of strongyloidiasis and the need for increased awareness.
Main Methods:
- Meta-analysis of 106 confirmed cases with detailed clinical information.
- Review of diagnostic methods including microscopic examination of feces, sputum, and urine.
- Inclusion of data from gastrointestinal endoscopy and other biopsy procedures.
Main Results:
- The overall case-fatality rate was 38%.
- Common symptoms included abdominal pain (53%), diarrhea (46%), fever (40%), and vomiting (39%).
- Diagnostic yield varied: parasite positivity in feces (75%), sputum (24%), urine (8%), and endoscopy/biopsy (17%).
Conclusions:
- Strongyloidiasis presents with non-specific symptoms, complicating early diagnosis and treatment.
- The disease is emerging in China, necessitating enhanced public and clinical vigilance.
- Improved prevention, control, and timely management strategies are required.
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