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Increased detection of elevated TSH using immunoradiometric assay

K Y Little1, K S Kearfott, X Castellanos

  • 1Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill.

Using a highly sensitive immunoradiometric assay, the authors detected an increased rate of elevated thyrotropin in 2,099 patients vs 1,789 patients examined with radioimmunoassay. Closer scrutiny of mood disorder patients with elevations found confirmatory evidence of thyroid dysfunction in most.

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