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Bacterial Gastroenteritis

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

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Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

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Inflammatory Bowel Disease I: Introduction

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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...

Cholera

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Related Experiment Video

Updated: May 13, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Deadly diarrhea: Clostridium difficile infection.

Carol Motes Headley¹

¹Memphis VA Medical Center, Nephrology, Memphis, TN, USA. carol.motes.headley@gmail.com

Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association

|March 9, 2013

Summary

Clostridium difficile infection causes severe diarrhea and is increasingly common, particularly in kidney failure patients. This article covers its diagnosis, treatment, and crucial infection control measures to prevent transmission.

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Last Updated: May 13, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Area of Science:

Infectious Diseases
Gastroenterology
Nephrology

Background:

Clostridium difficile infection (CDI) is a growing public health concern.
Patients with kidney failure face heightened risks for severe CDI.
Understanding CDI's epidemiology and clinical impact is crucial.

Observation:

CDI incidence and virulence are increasing.
Kidney disease is a significant risk factor for CDI.
Prompt diagnosis and effective treatment are vital.

Findings:

This article details CDI incidence, diagnosis, and treatment strategies.
It emphasizes the increased vulnerability of patients with kidney failure.
Specific infection control recommendations are provided to curb transmission.

Implications:

Implementing recommended infection control measures can reduce CDI spread.
Improved diagnostic and treatment protocols can mitigate CDI severity.
Raising awareness among healthcare providers and patients is essential for prevention.