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Updated: May 13, 2026

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
Published on: January 20, 2022
[Multimodal cardiovascular imaging before aortic valve transcatheter replacement]
L Davin1, P J Bruyère, P Lancellotti
1Service de Cardiologie-Imagerie cardio-vasculaire, CHU de Liège, Belgique. laurentdavin@yahoo.fr
Insights
Transcatheter aortic valve implantation (TAVI) offers an alternative for elderly patients with severe aortic stenosis who are poor surgical candidates. Careful imaging analysis ensures optimal bioprosthesis selection and guides alternative access routes when needed.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Severe calcified aortic valve stenosis is a prevalent valvular heart disease in developed nations.
- Symptomatic patients often face poor outcomes, with many denied traditional surgery due to age, comorbidities, or high surgical risk.
Purpose of the Study:
- To highlight Transcatheter Aortic Valve Implantation (TAVI) as a viable alternative for inoperable patients with severe aortic stenosis.
- To emphasize the importance of pre-procedural cardiac imaging for candidate selection and procedural planning.
Main Methods:
- Patient selection for TAVI based on clinical assessment and cardiac anatomy.
- Utilizing cardiac imaging modalities (echocardiography, CT, MRI) to assess feasibility and identify anatomical challenges.
- Considering alternative access routes (e.g., trans-subclavian, trans-apical) when retrograde approaches are contraindicated.
Main Results:
- TAVI provides a crucial treatment option for elderly patients with severe aortic stenosis deemed high-risk for surgery.
- Cardiac imaging is essential for determining appropriate aortic bioprosthesis size and identifying potential difficulties with standard access.
- Alternative access strategies ensure TAVI can be performed even with challenging vascular anatomy.
Conclusions:
- TAVI is a critical advancement for managing severe aortic stenosis in high-risk and elderly populations.
- Accurate pre-procedural imaging and consideration of alternative access routes are paramount for successful TAVI outcomes.
- This approach expands treatment options for valvular heart disease, improving patient management.
Abstract:
Calcified aortic valve stenosis is the most frequent valvular heart disease in developed countries with a very poor outcome when symptoms develop. However, several of these patients are denied for surgery. The main reasons are their advanced age (elderly patient), co-morbidities, technical limitations and a very high surgical risk. It is currently possible to propose a Transcatheter Aortic Valve Implantation (TAVI). After selection of candidates, the feasibility of the intervention is analysed. The size of the aortic bioprosthesis must be selected according to the cardiac anatomy. Several cardiac imaging modalities (echocardiography, computed tomography and cardiac MRI) can be used to identify unsuitable situations. Heavy calcifications or tortuosity can thwart the retrograde approach use. The sub-clavian arteries (for the CoreValve) and trans-apical approach (for the Edwards-Sapien) constitute alternatives ways.
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