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[Expression of GIRK4 gene in kidney tissues of obese rat]
Yong-an Kang1, Yan-rong Hu, Li Gao
1Hypertension Institute of Xinjiang, Urumqi, China.
Objective:
To investigate the expression of GIRK4 gene in the kidney tissues of obese rats.
Methods:
Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis.
Results:
The relative expression level of GIRK4 protein in the kidney tissues of obese rat (1.75±0.42) was significantly lower than that in normal rats (3.37±0.68, P<0.05).
Conclusion:
GIRK4 has a low protein expression in the kidney tissues of obese rat.
