Related Experiment Video
Updated: May 13, 2026

ATAC-Seq Library Preparation of Murine Bone Marrow-Derived Neutrophils
Published on: January 3, 2025
Technical note: proteomic approaches to fundamental questions about neutrophil biology
Kenneth R McLeish1, Michael L Merchant, Jon B Klein
11.Baxter I Research Bldg., Rm. 102 South, 570 South Preston St., Louisville, KY 40202, USA. k.mcleish@louisville.edu.
Abstract:
Proteomics is one of a group of technologies that generates high-throughput, large-scale datasets that can be used to understand cell or organ functions at a systems level. This review will focus on the application of proteomics to the understanding of neutrophil biology. The strengths and weaknesses of common proteomic methods and their application to neutrophils are reviewed, with the goal of evaluating whether the technology is ready to advance our understanding of neutrophil biology.

