Related Experiment Video

Updated: May 13, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Explaining temporal trends in annualised relapse rates in placebo groups of randomised controlled trials in relapsing

Simon M Steinvorth1, Christian Röver, Simon Schneider

  • 1Department of Medical Statistics, University Medical Center Göttingen, Germany.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|March 9, 2013
PubMed
Abstract

Keywords:
Multiple sclerosisannualised relapse ratebaseline characteristicsclinical study designeligibility criteriameta-analysismeta-regressionplacebo grouprelapsesystematic review

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