Related Experiment Video
Updated: May 13, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation of atrial fibrillation to reduce stroke risk
B Schmidt1, S Bordignon, A Fürnkranz
1Cardioangiologisches Centrum Bethanien, Wilhelm-Epstein Str. 4, 60431, Frankfurt am Main, Deutschland. b.schmidt@ccb.de
Insights
Catheter ablation can eliminate atrial fibrillation (AF), significantly reducing stroke risk. Discontinuing blood thinners after successful AF ablation may be safe for select patients with low stroke risk scores.
Area of Science:
- Cardiology
- Neurology
- Vascular Medicine
Background:
- Atrial fibrillation (AF) significantly elevates stroke risk, making it a major complication.
- Catheter ablation aims to eliminate AF, potentially reducing thromboembolic events.
- Existing research suggests stroke rates normalize post-ablation in AF patients.
Purpose of the Study:
- To evaluate the impact of catheter ablation on stroke risk in atrial fibrillation patients.
- To assess the safety and viability of discontinuing oral anticoagulation after successful AF ablation.
Main Methods:
- Review of studies investigating stroke rates after catheter ablation for AF.
- Analysis of patient outcomes based on CHA2DS2VASc scores and rhythm stability post-ablation.
Main Results:
- Successful catheter ablation normalizes stroke risk in AF patients, comparable to non-AF populations.
- Discontinuing anticoagulation post-ablation may be feasible for patients with a CHA2DS2VASc score < 2 and stable sinus rhythm.
Conclusions:
- Catheter ablation is effective in mitigating stroke risk associated with atrial fibrillation.
- Careful patient selection, considering stroke risk scores and rhythm stability, is crucial for safe anticoagulation discontinuation post-ablation.
Abstract:
Stroke is the most devastating complication of atrial fibrillation (AF), and the latter increases the risk of stroke by almost fivefold. AF elimination by catheter ablation should lower the risk of thromboembolic complications. Several studies support this hypothesis, demonstrating rates of stroke in AF patients similar to non-AF populations after successful catheter ablation. Widespread discontinuation of oral anticoagulation after catheter ablation is currently not supported by scientific data but it may be a viable option for patients with a CHA2DS2VASc score of less than 2 and a well-documented stable sinus rhythm.
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization III: Left Heart Catheterization
Cardiopulmonary Resuscitation III: AED Use

