Related Experiment Video

Updated: Aug 17, 2026

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

Congenital dislocation of the hip in Ehlers-Danlos syndrome

O Badelon1, H Bensahel, Z Csukonyi

  • 1Department of Pediatric Orthopaedic Surgery, Hospital Robert Debré, Bichat University Medical School, Paris, France.

Clinical Orthopaedics and Related Research
|June 1, 1990
PubMed

Insights

Congenital hip dislocation in Ehlers-Danlos syndrome (EDS) patients is challenging. Surgical intervention, including osteotomies, is often required for successful treatment and stabilization.

Area of Science:

  • Orthopedics
  • Genetics
  • Pediatric Surgery

Background:

  • Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders.
  • Congenital dislocation of the hip (CDH) is a complex orthopedic condition.
  • EDS can complicate the management of CDH due to tissue fragility.

Purpose of the Study:

  • To evaluate the treatment outcomes for congenital dislocation of the hip (CDH) in patients with Ehlers-Danlos syndrome (EDS).
  • To identify challenges and necessary surgical approaches for managing CDH in this specific patient population.

Main Methods:

  • Retrospective analysis of nine patients diagnosed with EDS and bilateral CDH.
  • Initial treatment involved closed reduction for eight patients, with subsequent surgical interventions.
  • Total of 42 surgical procedures performed across all patients.

Main Results:

  • Avascular necrosis of the femoral head occurred in five hips, predominantly after closed reduction.
  • Clinical success was achieved in 12 of 16 hips, while radiographic success was noted in only six.
  • Significant surgical interventions, including femoral and innominate osteotomies, were required for stabilization.

Conclusions:

  • Managing CDH in EDS patients presents significant challenges requiring specialized surgical techniques.
  • Femoral and innominate osteotomies are crucial for achieving and maintaining hip reduction in EDS patients with CDH.
  • Early and aggressive surgical management may be necessary to improve outcomes.

More Related Videos

Imaging of the Microstructural Failure Mechanism in the Human Hip08:43

Imaging of the Microstructural Failure Mechanism in the Human Hip

Published on: September 29, 2023

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia08:40

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Published on: April 19, 2024

Related Concept Videos

Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Desmosomes01:05

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Hiatal Hernia01:25

Hiatal Hernia

A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...