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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Obstetrical acute renal failure: a challenging medical complication
Naushaba Rizwan1, Syed Farhan Uddin
1Department of Obstetrics and Gynaecology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan. naushabarizwansyed@yahoo.com
Journal of Ayub Medical College, Abbottabad : JAMC
|March 12, 2013
Summary
Pregnancy-related acute renal failure (ARF) affects 1.065% of obstetric admissions. This dangerous complication carries high maternal and fetal mortality, with postpartum hemorrhage being a leading cause.
Area of Science:
- Obstetrics and Gynecology
- Nephrology
- Critical Care Medicine
Background:
- Acute renal failure (ARF) is a rapid decline in kidney function, leading to waste product buildup.
- Obstetrical renal failure is a critical complication of pregnancy.
- Understanding its prevalence, risk factors, and outcomes in women is crucial.
Purpose of the Study:
- To determine the prevalence of pregnancy-related acute renal failure.
- To identify risk factors associated with obstetrical ARF.
- To analyze the outcomes, including mortality and morbidity, in affected women.
Main Methods:
- An observational study conducted at Liaquat University Hospital, Pakistan (Oct 2009-Sep 2010).
- Included 35 patients with obstetrical ARF, excluding those with chronic conditions.
- Utilized detailed history, physical examination, laboratory tests, and imaging (renal scan, ultrasonography, biopsy) when needed.
Main Results:
- Pregnancy-related ARF occurred in 1.065% of 3,285 obstetric admissions.
- Leading causes included postpartum hemorrhage (31.42%), antepartum hemorrhage (25.71%), eclampsia (17.14%), DIC (14.28%), and sepsis (11.42%).
- Maternal mortality was 25.71%, fetal mortality was 22.85%, and 53% of patients achieved complete recovery.
Conclusions:
- Pregnancy-related ARF is a significant cause of acute renal failure in obstetric populations.
- It is a dangerous complication associated with high maternal and fetal mortality.
- Prompt identification and management are vital to improve outcomes.
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