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Disseminated intravascular coagulation

Humaira Naz1, Anisa Fawad, Ansa Islam

  • 1Department of Obstetrics and Gynaecology, Ayub Medical College, Abbottabad, Pakistan. drmaira@hotmail.com

Journal of Ayub Medical College, Abbottabad : JAMC
|March 12, 2013
PubMed

Insights

Disseminated Intravascular Coagulation (DIC) affects 0.92% of obstetrical admissions. Promptly addressing underlying causes is crucial for managing this life-threatening thrombohaemorrhagic disorder.

Area of Science:

  • Obstetrics and Gynecology
  • Hematology
  • Critical Care Medicine

Background:

  • Disseminated Intravascular Coagulation (DIC) is a severe thrombohaemorrhagic disorder.
  • It is characterized by widespread endothelial damage.
  • The study aimed to determine DIC prevalence in obstetrical conditions.

Purpose of the Study:

  • To assess the prevalence of Disseminated Intravascular Coagulation (DIC) in various obstetric scenarios.
  • To identify associated risk factors and evaluate maternal and fetal outcomes in these cases.

Main Methods:

  • A descriptive study was conducted over two years (2010-2011).
  • Included 40 diagnosed cases of DIC among 4,334 obstetrical admissions.
  • Evaluated risk factors and maternal/fetal outcomes.

Main Results:

  • DIC prevalence was 0.92% (40/4334 admissions).
  • Eclampsia (70%) and abruptio placentae (17.5%) were primary risk factors.
  • Maternal mortality was 25% and perinatal mortality was 47.5%.

Conclusions:

  • DIC is a critical, life-threatening condition linked to underlying pathologies.
  • Resolution of DIC is often spontaneous following correction of the primary cause.
Abstract

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