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Related Experiment Video

Updated: May 13, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

Disseminated intravascular coagulation.

Humaira Naz¹, Anisa Fawad, Ansa Islam

¹Department of Obstetrics and Gynaecology, Ayub Medical College, Abbottabad, Pakistan. drmaira@hotmail.com

Journal of Ayub Medical College, Abbottabad : JAMC

|March 12, 2013

Summary

Disseminated Intravascular Coagulation (DIC) affects 0.92% of obstetrical admissions. Promptly addressing underlying causes is crucial for managing this life-threatening thrombohaemorrhagic disorder.

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Area of Science:

Obstetrics and Gynecology
Hematology
Critical Care Medicine

Background:

Disseminated Intravascular Coagulation (DIC) is a severe thrombohaemorrhagic disorder.
It is characterized by widespread endothelial damage.
The study aimed to determine DIC prevalence in obstetrical conditions.

Purpose of the Study:

To assess the prevalence of Disseminated Intravascular Coagulation (DIC) in various obstetric scenarios.
To identify associated risk factors and evaluate maternal and fetal outcomes in these cases.

Main Methods:

A descriptive study was conducted over two years (2010-2011).
Included 40 diagnosed cases of DIC among 4,334 obstetrical admissions.
Evaluated risk factors and maternal/fetal outcomes.

Main Results:

DIC prevalence was 0.92% (40/4334 admissions).
Eclampsia (70%) and abruptio placentae (17.5%) were primary risk factors.
Maternal mortality was 25% and perinatal mortality was 47.5%.

Conclusions:

DIC is a critical, life-threatening condition linked to underlying pathologies.
Resolution of DIC is often spontaneous following correction of the primary cause.