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Updated: May 13, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Depression, pain, and comorbid medical conditions
J Sloan Manning1, W Clay Jackson
1University of North Carolina, Chapel Hill, NC, USA.
Abstract:
Depression commonly co-occurs with medical illnesses and chronic pain, which can contribute to the somatic symptoms of depression, complicate diagnosis and treatment, worsen patients' prognosis, and hinder recovery. Many therapies are available to treat depression, but patients with depression and pain or medical conditions may require a different treatment strategy than those with depression alone. This activity focuses on the best methods for recognizing and diagnosing these conditions, selecting appropriate therapies to create comprehensive treatment plans, and monitoring and educating patients to improve their quality of life.
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