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Related Concept Videos

Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...
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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Encephalitis l: Introduction01:19

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Cerebral Edema ll: Pathophysiology01:22

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Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

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Posterior reversible encephalopathy syndrome.

Courtney M Schusse1, Alicia L Peterson, Jason P Caplan

  • 1Department of Neurology, Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.

Psychosomatics
|March 12, 2013
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Summary

Posterior reversible encephalopathy syndrome (PRES) causes neuropsychiatric symptoms and cerebral edema. Early recognition and diagnosis are crucial for managing this under-recognized condition and preventing severe outcomes.

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Area of Science:

  • Neurology
  • Radiology
  • Psychiatry

Background:

  • Posterior reversible encephalopathy syndrome (PRES) is a neurological condition characterized by neuropsychiatric symptoms and cerebral edema.
  • It is associated with a variety of underlying clinical conditions.

Observation:

  • PRES typically presents with symptoms mimicking delirium.
  • Two cases of PRES are presented to illustrate the condition.

Findings:

  • PRES can arise from diverse etiologies.
  • The hallmark of PRES is reversible white matter edema on neuroimaging.

Implications:

  • General hospital psychiatrists must be aware of PRES presentation and diagnostic strategies.
  • Timely diagnosis and management of PRES can prevent serious sequelae.