Related Experiment Video
Updated: May 13, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
The pedicled inferior paraumbilical perforator (I-PUP) flap for a volar wrist defect: a reconstructive solution
L Shukla1, G I Taylor, R Shayan
1Plastic and Reconstructive Surgery Unit, Department of Surgery, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia; AORTEC Unit, Faculty of Health Science, Australian Catholic University, O'Brien Institute, Fitzroy, Victoria 3065, Australia.
Abstract:
Full-thickness soft-tissue defects overlying vital forearm or wrist structures frequently result from acute trauma or tumor ablation. These defects present reconstructive challenges, due to the thin pliable skin to be replaced and the non-graftable bed beneath. The authors discuss a case of a renal-transplant patient with a volar wrist SCC, in whom local vascular anatomy deemed microvascular free tissue transfer inappropriate. The authors present a successful novel reconstructive solution; the pedicled inferior paraumbilical perforator flap (I-PUP), a two-staged procedure that incorporates principles of distant flaps--which pre-date microsurgery--combined with techniques and lessons learned in the era of perforator flap surgery.
