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Updated: May 13, 2026
08:44
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Cervical unicentric Castleman's disease in children
J Bouguila1, I Lahmer1, M Abdelkefi2
1Service de pédiatrie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisia.
Summary
Unicentric Castleman
Area of Science:
- Pediatric Pathology
- Surgical Oncology
Background:
- Unicentric Castleman's disease (CD) is a rare, benign lymphoproliferative condition.
- Cervical location of unicentric CD is infrequently documented in pediatric cases.
Observation:
- A 13-year-old male presented with a 3-month history of a right neck mass.
- Physical examination identified a 5 cm mobile node within the sternocleidomastoid muscle.
- Hyaline vascular type CD was diagnosed post-surgical excision and histopathology.
Findings:
- Complete surgical resection led to a favorable outcome.
- No recurrence was observed during a 1-year follow-up period.
Implications:
- Cervical masses in children may represent Castleman's disease, though rare.
- Histopathological examination is crucial for definitive diagnosis.
- Complete excision of hyaline vascular type unicentric CD offers a good prognosis.
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