Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Systemic and Pulmonary Circulation01:15

Overview of Systemic and Pulmonary Circulation

The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Impact of Guideline-Directed Medical Therapy in Patients with Left Ventricular Assist Device: An International Multicenter Study.

ESC heart failure·2026
Same author

Determinants and outcomes of late electrical storm in patients supported by left ventricular assist device.

Heart rhythm·2026
Same author

Tetralogy of Fallot: electrophysiology-guided surgical ablation during pulmonary valve replacement.

European heart journal·2026
Same author

Isolated extravascular implantable cardioverter-defibrillator infection without leadless pacemaker involvement: A unique dual-device case report.

HeartRhythm case reports·2026
Same author

Duration of heart failure as a determinant of outcomes after left ventricular assist device implantation: an international multicenter study.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Predictors of Long-Term Outcomes in Hypertrophic Cardiomyopathy: The NHLBI HCM Registry.

JAMA·2026
Same journal

Neighborhood-Level Material Resources and Risk of Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease.

The Canadian journal of cardiology·2026
Same journal

Storm Clouds Coming: Red-Flag Warning for Hypertension Prevalence and Control in the Post-COVID-19 Era.

The Canadian journal of cardiology·2026
Same journal

Universal coverage, unequal care: Why Canada needs a national cardiovascular access ledger.

The Canadian journal of cardiology·2026
Same journal

Prolonged Loop Recorder Retention: Safety, Diagnostic Yield, and the Case for Community-Based Explantation.

The Canadian journal of cardiology·2026
Same journal

Multimodality Fusion Imaging of Subclinical Systemic Right Ventricular Remodeling in Congenitally Corrected Transposition of the Great Arteries.

The Canadian journal of cardiology·2026
Same journal

Percutaneous Coronary Intervention Prior to Transcatheter Aortic Valve Implantation: A Bayesian Meta-Analysis of Randomized Controlled Trials.

The Canadian journal of cardiology·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

Fontan circulation: success or failure?

Blandine Mondésert1, François Marcotte, François-Pierre Mongeon

  • 1Montreal Heart Institute Adult Congenital Center, Université de Montréal, Montreal, Québec, Canada.

The Canadian Journal of Cardiology
|March 12, 2013
PubMed
Summary
This summary is machine-generated.

Fontan surgery enables survival for children with severe congenital heart defects but leads to hemodynamic compromise. Ongoing research is crucial for managing Fontan circulation failure and its complications.

More Related Videos

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
10:10

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail

Published on: February 3, 2016

Related Experiment Videos

Last Updated: May 13, 2026

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
10:10

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail

Published on: February 3, 2016

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Fontan surgery is a critical intervention for single-ventricle congenital heart defects, allowing survival into adulthood.
  • The Fontan circulation, while life-saving, presents inherent hemodynamic challenges and risks multiorgan complications.

Purpose of the Study:

  • To review the pathophysiology, clinical manifestations, and therapeutic options for failing Fontan circulation.
  • To highlight the progressive decline in efficiency and age-related complications associated with the Fontan physiology.

Main Methods:

  • Review of current knowledge on Fontan circulation pathophysiology.
  • Categorization of Fontan failure into ventricular dysfunction, systemic complications, and chronic failure.

Main Results:

  • Fontan circulation failure encompasses ventricular dysfunction, systemic issues, and chronic decline.
  • The Fontan circulation's efficiency diminishes with age, necessitating ongoing management.

Conclusions:

  • Fontan patients require continuous support and management due to the dynamic and declining nature of the circulation.
  • Further research into therapies for univentricular dysfunction and systemic complications, including mechanical support, is essential.