Related Experiment Video
Updated: May 13, 2026

Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling
Published on: August 19, 2017
Reactive lymphoid hyperplasia of the pancreas: a clinical conundrum
Thalis Christophides1, Adam E Frampton, Patrizia Cohen
1HPB Surgical Unit, Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, Hammersmith Hospital campus, London, United Kingdom.
Context:
Localized reactive lymphoid hyperplasia is a rare condition characterized by the presence of lymphoid follicles.
Case Report:
We describe a case of a 60-year-old woman who presented with right upper quadrant pain and was found to have a reactive nodular hyperplasia of the pancreas involving the uncinate process, body and tail of the gland. Due to the multifocal distribution of these hypoechoic vascular lesions, a total pancreatectomy was performed since malignancy could not be safely excluded.
Conclusion:
There have been a handful of cases reporting reactive lymphoid hyperplasia affecting the pancreas; however, it is uncommon to perform such a radical pancreatic resection for this benign condition.
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