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Published on: November 5, 2019
Surveillance of bacterial meningitis in the country of Georgia, 2006-2010
Maia Butsashvili1, George Kandelaki, Medea Eloshvili
1National Center for Diseases Control and Public Health, 9 Asatiani Str., 0177 Tbilisi, Georgia. maiabutsashvili@gmail.com
Insights
Bacterial meningitis is a significant global health threat. Streptococcus pneumoniae was the most common cause in Georgia, with high mortality rates, especially for TB meningitis.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Bacterial meningitis causes significant global morbidity and mortality, especially in developing nations.
- Surveillance data is crucial for understanding causative agents and improving outcomes.
Purpose of the Study:
- To analyze bacterial meningitis epidemiology in Georgia from 2006-2010.
- To identify common pathogens and their associated mortality rates.
Main Methods:
- Sentinel surveillance of hospitalized patients with suspected bacterial meningitis in Tbilisi, Georgia.
- Laboratory confirmation and etiological agent identification.
- Analysis of case fatality rates.
Main Results:
- 127 patients (19%) had identified causative organisms.
- Streptococcus pneumoniae (52.8%) was the most frequent pathogen, followed by Haemophilus influenzae (13.4%) and Neisseria meningitidis (12.6%).
- Tuberculosis (TB) meningitis was suspected in 21.3% of cases, with the highest mortality (22.2%).
Conclusions:
- Streptococcus pneumoniae is a primary cause of bacterial meningitis in Georgia.
- High mortality rates associated with TB meningitis and Neisseria meningitidis require targeted interventions.
- Effective surveillance is vital for controlling bacterial meningitis in vulnerable populations.
Abstract:
Bacterial meningitis remains important cause of morbidity and mortality worldwide, particularly in developing countries. This study analyzed the data from sentinel surveillance for bacterial meningitis among children <5 years of age hospitalized in largest children's hospital in Tbilisi, capital of Georgia and adult patients hospitalized in infectious diseases hospital during 2006-2010 with suspected bacterial meningitis. The surveillance is conducted by National Center for Disease Control and Public Health (NCDCPH). The number of patients with identified organism was 127 (19 %). In the subsample of patients with laboratory confirmed bacterial meningitis Streptococcus pneumoniae was the most frequently isolated organism (67 cases, 52.8 %), followed by. influenza (17 cases, 13.4 %) and Neisseria meningitidis (16 cases, 12.6 %). The number of patients with suspected TB meningitis was 27 (21.3 %). The overall case fatality rate in the subgroup of patients with identified organism was 12.3 %. The highest mortality was observed among TB patients (22.2 %) with 14.3 % mortality for N. meningitidis and 10.3 % for S. pneumoniae. No lethal outcome was observed among patients with Haemophilus influenzae.
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