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Updated: May 13, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

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8-Meth-oxy-2H-chromene-3-carbaldehyde.

¹Department of Applied Chemistry, Dongduk Women's University, Seoul 136-714, Republic of Korea.

Acta Crystallographica. Section E, Structure Reports Online

|March 12, 2013

Summary

This study details the molecular structure of C11H10O3, revealing a specific half-chair conformation of its fused dihydro-pyran ring. Molecular analysis also identified weak C-H⋯O hydrogen bonds facilitating crystal structure linkage.

Area of Science:

Crystallography
Organic Chemistry
Molecular Structure Analysis

Background:

Understanding molecular conformation is crucial in organic chemistry.
Dihydro-pyran ring systems are common motifs in various organic compounds.
Crystal packing influences material properties.

Purpose of the Study:

To elucidate the precise three-dimensional structure of the molecule C11H10O3.
To characterize the conformation of the fused dihydro-pyran ring.
To investigate intermolecular interactions within the crystal lattice.

Main Methods:

Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
Analysis of atomic positions and bond lengths/angles.

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Identification of hydrogen bonding networks.

Main Results:

The fused dihydro-pyran ring adopts a half-chair conformation.
The oxygen atom and a methylene carbon atom deviate from the mean plane of the ring.
Weak C-H⋯O hydrogen bonds were observed, linking molecules along the [001] direction.

Conclusions:

The study provides detailed structural information for C11H10O3.
The observed conformation and hydrogen bonding offer insights into the molecule's behavior in the solid state.
This structural data can be valuable for further synthetic or computational studies.