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Updated: May 13, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-N'-(4-Meth-oxy-benzyl-idene)-2-m-tolyl-acetohydrazide
A S Praveen1, Jerry P Jasinski, Amanda C Keeley
1Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570 006, India.
Acta Crystallographica. Section E, Structure Reports Online
|March 12, 2013
Summary
The crystal structure of C17H18N2O2 reveals benzene rings with a dihedral angle of 83.0°. Molecules form dimers via hydrogen bonds and are linked into columns by weak interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding molecular interactions is crucial for materials science.
- Crystal engineering aims to design materials with specific properties.
- Intermolecular forces dictate the solid-state structure of organic molecules.
Purpose of the Study:
- To elucidate the crystal structure of the molecule C17H18N2O2.
- To investigate the intermolecular interactions governing its solid-state assembly.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding and other non-covalent interactions was performed.
- Graph-set notation was used to characterize hydrogen bond motifs.
Main Results:
- The crystal structure of C17H18N2O2 was determined, with a significant dihedral angle of 83.0° between benzene rings.
- N-H⋯O hydrogen bonds formed centrocymmetric dimers with an R(2)2(8) graph-set motif.
- Weak C-H⋯π interactions further organized these dimers into [100] columns.
Conclusions:
- The study provides detailed structural information for C17H18N2O2.
- Hydrogen bonding and C-H⋯π interactions are key in directing the supramolecular assembly.
- The findings contribute to the understanding of crystal packing in organic molecules.
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