Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

IUPAC Nomenclature of Aldehydes

IUPAC Nomenclature of Aldehydes

Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...

Oxymercuration-Reduction of Alkenes

Oxymercuration-Reduction of Alkenes

Oxymercuration–reduction of alkenes is one of the major reactions converting alkenes to alcohols. It involves the hydration of alkenes with mercuric acetate in a mixture of tetrahydrofuran and water, forming an organomercury adduct. This is followed by a demercuration step in which the adduct is reduced to an alcohol using sodium borohydride.

Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation

Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation

Baeyer–Villiger oxidation converts aldehydes to carboxylic acids and ketones to esters. The reaction uses peroxy acids or peracids and is often catalyzed by acid. The reaction is named after its pioneers, Adolf von Baeyer and Victor Villiger. The reaction is achieved by a wide range of peracids such as m-chloroperoxybenzoic acid (mCPBA), perbenzoic acid (C6H5COOOH), peracetic acid (CH3COOOH), hydrogen peroxide (H2O2), and tert-butyl hydroperoxide (t-BuOOH).
The carbonyl center is activated by...

Common Names of Aldehydes and Ketones

Common Names of Aldehydes and Ketones

Some common aldehydes and ketones are popularly known by their common names used historically and predate the IUPAC nomenclature.
Common names of aldehydes are derived from the names of their corresponding acid. For instance, the two-carbon aldehyde–acetaldehyde derives its name from the corresponding acid–acetic acid. Similarly, formaldehyde derives its name from formic acid and benzaldehyde from benzoic acid.
Aliphatic ketones are named by suffixing the word “ketone” to the alphabetically...

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.

Hydroboration-Oxidation of Alkenes

Hydroboration-Oxidation of Alkenes

In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Design and Analysis of the Dual-Band Far-Field Super-Resolution Metalens with Large Aperture.

Nanomaterials (Basel, Switzerland)·2024

Same author

Ultra short term power load forecasting based on the fusion of Seq2Seq BiLSTM and multi head attention mechanism.

PloS one·2024

Same author

An efficient genetic transformation system mediated by Rhizobium rhizogenes in fruit trees based on the transgenic hairy root to shoot conversion.

Plant biotechnology journal·2024

Same author

Notoginsenoside R1 targets PPAR-γ to inhibit hepatic stellate cell activation and ameliorates liver fibrosis.

Experimental cell research·2024

Same author

Investigating the epidemiological relevance of secretory otitis media and neighboring organ diseases through an Internet search.

PeerJ·2024

Same author

Untargeted urine metabolomics and machine learning provide potential metabolic signatures in children with autism spectrum disorder.

Frontiers in psychiatry·2024

Search research articles

Related Experiment Video

Updated: May 13, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Published on: January 19, 2016

4-Meth-oxy-3-(meth-oxy-meth-yl)benzalde-hyde.

Jing-Chao Zhang¹, Jun Sun, Juan Zhang

¹Department of Applied Chemistry, College of Science, Nanjing University of Technology, Nanjing 211816, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online

|March 12, 2013

Summary

This study details the molecular structure of a specific organic compound (C10H12O3). Researchers analyzed the dihedral angle and atomic deviations, revealing weak intermolecular interactions like C-H⋯π bonds.

More Related Videos

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups

Published on: October 3, 2025

Related Experiment Videos

Last Updated: May 13, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Published on: January 19, 2016

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups

MALDI-ToF MS Method for the Characterization of Synthetic Polymers with Varying Dispersity and End Groups

Published on: October 3, 2025

Area of Science:

Organic Chemistry
Crystallography

Background:

Understanding the precise three-dimensional arrangement of atoms in organic molecules is crucial for predicting their properties and reactivity.
The study of intermolecular forces helps elucidate the bulk behavior of crystalline solids.

Purpose of the Study:

To determine the crystal structure of the title compound, C10H12O3.
To analyze the spatial relationship between the benzene ring and its methoxy-methyl side chain.
To identify and characterize intermolecular interactions within the crystal lattice.

Main Methods:

Single-crystal X-ray diffraction was employed to obtain detailed structural information.
Analysis of atomic coordinates and bond lengths/angles provided geometric insights.
Intermolecular interactions were identified through crystallographic analysis.

Main Results:

The dihedral angle between the benzene ring and the methoxy-methyl side chain was found to be 9.7(2)°.
The oxygen atom of the aldehyde group and the carbon atom of the methoxy group showed minimal deviation from the benzene ring plane (0.039(3) Å and 0.338(4) Å, respectively).
The crystal structure is characterized by very weak C-H⋯π intermolecular interactions as the primary mode of association.

Conclusions:

The title compound exhibits a specific conformation influenced by the steric and electronic nature of the methoxy-methyl side chain.
The weak C-H⋯π interactions suggest a loosely packed crystal structure.
These findings contribute to the understanding of structure-property relationships in substituted aromatic compounds.