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Updated: May 13, 2026

11:51
Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
8-Hy-droxy-5,7-dimethyl-quinolin-1-ium chloride dihydrate
Kaliyaperumal Thanigaimani1, Nuridayanti Che Khalib, Suhana Arshad
1School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
Acta Crystallographica. Section E, Structure Reports Online
|March 12, 2013
Abstract:
In the title hydrated salt, C11H12NO(+)·Cl(-)·2H2O, the quinoline ring system is essentially planar, with a maximum deviation of 0.005 (1) Å for all non-H atoms. In the crystal, the three components are linked by O-H⋯O, N-H⋯O, O-H⋯Cl and weak C-H⋯O hydrogen bonds, forming a layer structure parallel to the ac plane. The crystal structure is further stabilized by π-π stacking inter-actions, with centroid-centroid distances of 3.5213 (6) and 3.7176 (6) Å.

