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Updated: May 13, 2026

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
2-[3-Meth-oxy-5-(pyrimidin-2-yl)phen-yl]pyrimidine
Jiena Hu1, Yang Wu, Dengqing Zhang
1College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, 2999 North Renmin Road, Songjiang, Shanghai 201620, People's Republic of China.
Abstract:
The title compound, C15H12N4O, was synthesized by a standard Suzuki cross-coupling reaction. The terminal pyrim-idine rings are rotated at dihedral angles of 12.06 (4) and -13.13 (4)° with respect to the central benzene ring. In the crystal, the mol-ecules are connected by two kinds of C-H⋯N hydrogen bonds, forming zigzag chains along the c axis. Weak π-π inter-actions between the benzene and one of the pyrimidine rings are also found and stack the mol-ecules along the b axis [centroid-centroid distance = 4.112 (3) Å].
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