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Updated: May 13, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Ethyl 5-bromo-3-eth-oxy-carbonyl-amino-1-benzofuran-2-carboxyl-ate
Prashantha Karunakar1, V Krishnamurthy, C R Girija
1Department of Biotechnology, PES Institute of Technology, BSK III Stg, Bangalore 560 085, India.
Abstract:
In the title compound, C14H14BrNO5, the ester group is disordered [occupancy ratio 0.52 (2):0.48 (2)]. The major component is nearly coplanar with the benzofuran plane, subtending a dihedral angle of 7.84 (2)°, while the amide group is twisted out of the benzofuran plane making a dihedral angle of 39.69 (2)°. An intra-molecular N-H⋯O hydrogen bond occurs. In the crystal, pairs of weak C-H⋯O hydrogen bonds link the mol-ecules into inversion dimers, which are further linked via strong N-H⋯O hydrogen bonds, generating a zigzag chain extending along [100].
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