Related Experiment Video
Updated: May 13, 2026
Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
6,7-Difluoro-1,2,3,4-tetra-hydro-quin-oxa-line-5,8-dicarbonitrile
Bao-Hua Qu1, Xiao-Chuan Jia, Jing Li
1Key Laboratory of Fine Petrochemical Technology, Changzhou University, Changzhou 213164, People's Republic of China.
Abstract:
In the title compound, C10H6F2N4, the Car-N bonds are slightly shortened with respect to a standard aniline C-N bond [1.3580 (16) and 1.3618 (16) versus 1.39 Å], thus indicating some π-π conjgation with the electron-acceptor CN groups. The mol-ecule, except for two C atom of the ethyl-ene bridge, is nearly planar, the largest deviation of the other non-H atoms from the mean plane being 0.309 (2) Å. The N-C-C-N torsion angle involving the ethyl-ene bridge is 50.23 (18)°. In the crystal, mol-ecules are connected by pairs of N-H⋯N hydrogen bonds into chains along [21-1].
Related Concept Videos
01:11Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
02:36Acidity and Basicity of Alcohols and Phenols