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Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

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Updated: May 13, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

Occupational asthma often goes unrecognised.

Paul Cullinan¹, Julie Cannon

¹Royal Brompton Hospital, London, UK.

The Practitioner

|March 13, 2013

Summary

Occupational asthma, triggered by workplace agents, affects fit young adults and is often missed. Differentiating it from work-exacerbated asthma is crucial for proper management and legal reasons.

Area of Science:

Allergy and Immunology
Occupational Health
Respiratory Medicine

Background:

Occupational asthma (OA) is a de novo condition caused by workplace airborne agents.
Work-exacerbated asthma (WEA) involves pre-existing asthma triggered by workplace irritants.
Distinguishing OA from WEA is critical due to differing clinical, occupational, and legal implications.

Purpose of the Study:

To highlight the underrecognition of occupational asthma, particularly in young, otherwise healthy individuals.
To emphasize the importance of considering OA and WEA in working adults presenting with asthma or suggestive symptoms like rhinitis.
To outline key diagnostic features differentiating OA from WEA.

Main Methods:

Review of the clinical presentation and diagnostic criteria for occupational asthma.

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Emphasis on the role of immediate-type hypersensitivity reactions to workplace sensitizers.

Discussion of symptom patterns, including improvement away from work and latency period.

Main Results:

Occupational asthma often develops within 6–36 months of new employment.
Rhinitis is a common symptom in OA, and its absence may rule out the condition in environments with airborne proteins.
Symptoms of OA typically improve when away from the workplace.

Conclusions:

Occupational asthma is frequently underdiagnosed, often mistaken for common ailments like colds or hay fever.
A thorough occupational history, including symptom improvement away from work, is essential for diagnosing OA.
Early consideration of OA and WEA in working adults with respiratory symptoms can lead to timely diagnosis and intervention.