Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Second edition of the "do not do" recommendations from the Spanish Society of Endocrinology and Nutrition (SEEN).

Endocrinologia, diabetes y nutricion·2025
Same author

Barriers and Strategies to Optimize the Use of Glucagon-Like Peptide 1 Receptor Agonists in People with Type 2 Diabetes and High Cardiovascular Risk or Established Cardiovascular Disease: A Delphi Consensus in Spain.

Advances in therapy·2024
Same author

Application of the changes in the Standards of Medical Care in Diabetes ADA 2021 to clinical practice in our country. SED-SEEN document.

Endocrinologia, diabetes y nutricion·2021
Same author

Application of the changes in the Standards of Medical Care in Diabetes ADA 2021 to clinical practice in our country. SED-SEEN document.

Endocrinologia, diabetes y nutricion·2021
Same author

Influenza vaccination in endocrine disease. Is it in our mind?

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion·2013
Same author

[FESNAD-SEEDO consensus summary: evidence-based nutritional recommendations for the prevention and treatment of overweight and obesity in adults].

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion·2012

Related Experiment Video

Updated: May 13, 2026

In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse
04:14

In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse

Published on: October 6, 2023

Hyperthyroidism and pregnancy.

Manuel Gargallo Fernández1

  • 1Unidad de Endocrinología y Nutrición, Hospital Virgen de la Torre, Madrid, España.

Endocrinologia Y Nutricion : Organo De La Sociedad Espanola De Endocrinologia Y Nutricion
|March 13, 2013
PubMed
Summary
This summary is machine-generated.

Hyperthyroidism during pregnancy requires specialized care for mother and baby. Management differs from non-pregnant cases, presenting unique diagnostic and therapeutic challenges for thyroid disorders.

Keywords:
EmbarazoEnfermedad de GravesGestational transient thyrotoxicosisGraves’ diseaseHiperemesis gravídicaHipertiroidismoHyperemesis gravidarumHyperthyroidismPregnancyTirotoxicosis gestacional transitoria

Related Experiment Videos

Last Updated: May 13, 2026

In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse
04:14

In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse

Published on: October 6, 2023

Area of Science:

  • Endocrinology
  • Maternal-Fetal Medicine
  • Reproductive Health

Background:

  • Hyperthyroidism in pregnancy is a common occurrence with significant implications for maternal and fetal well-being.
  • Postpartum complications can affect both the newborn and the nursing mother.
  • Managing hyperthyroidism during pregnancy presents distinct diagnostic and therapeutic challenges compared to non-pregnant individuals.

Purpose of the Study:

  • To review the unique biochemical assessment of thyroid function in pregnant individuals.
  • To discuss potential causes of hyperthyroidism during pregnancy.
  • To outline the clinical and therapeutic strategies for managing hyperthyroidism in pregnancy, with a focus on Graves' disease.

Main Methods:

  • Literature review of studies on hyperthyroidism in pregnancy.
  • Analysis of biochemical assessment specific to pregnancy.
  • Examination of clinical and therapeutic approaches for various causes of hyperthyroidism.
  • Detailed review of Graves' disease in pregnancy and its consequences.

Main Results:

  • Thyroid function tests require specific interpretation during pregnancy.
  • Graves' disease is a common cause, necessitating careful management to mitigate maternal, fetal, and neonatal risks.
  • Tailored therapeutic strategies are crucial for optimal outcomes.

Conclusions:

  • Effective management of hyperthyroidism in pregnancy hinges on understanding unique physiological changes and specific etiologies.
  • Addressing maternal, fetal, neonatal, and postnatal aspects is vital for successful outcomes.
  • Special attention to Graves' disease management is essential due to its potential complications.