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Updated: May 13, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Fluid structure interaction simulation in three-layered aortic aneurysm model under pulsatile flow: comparison of
Feng Gao1, Hiroshi Ueda, Li Gang
1Department of Mechanical Engineering, Faculty of Engineering and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan. wind.fgao@gmail.com
Abstract:
One treatment method for aortic aneurysm is the invasive insertion of a stent into the aneurysm. Another method is wrapping the aneurysm using newly developed expanded polytetrafluoroethylene (PTFE) material. A virtual stented aneurysm model and a wrapped aneurysm model were created to study the flow and wall dynamics by means of fluid-structure interaction analyses. The flow velocity and pressure distribution as well as the deformation and wall stress were investigated. Stenting significantly changed the blood flow pattern and the vortexes in the aneurysm. Wrapping increased the thickness of the aneurysm wall and increased the strength of the vessel wall. The maximum von Mises stress in the stented model was found to be 220,494 Pa and 228,218 Pa at the time of peak flow and peak pressure, respectively. This was reduced by 37.8% and 36.7% to 137,200 and 144,354 Pa, respectively, in the wrapped model. Our results provide information that may improve the understanding of the biomechanics of stenting and wrapping.
