Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Update on the comparative <i>in vitro</i> activity of cefiderocol and four β-lactam-β-lactamase-inhibitor combinations against clinically important Gram-negative pathogens.

JAC-antimicrobial resistance·2026
Same author

Attitude and perception toward artificial intelligence among German physicians with intensive care experience: a survey study.

Frontiers in health services·2026
Same author

Impact of enhanced infection control and antimicrobial stewardship on infections by Clostridioides difficile, vancomycin-resistant enterococci, and third-generation cephalosporin-resistant Enterobacterales: a stepped-wedge cluster intervention study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2025
Same author

A very rare case of osseous involvement of the dens axis in a 52-year-old HIV positive patient as part of secondary syphilis.

Infection·2025
Same author

[Empirical antibiotic therapy in life-threatening infections-current concepts and controversies].

Die Anaesthesiologie·2025
Same author

The Europa Imaging System (EIS) Investigation.

Space science reviews·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
See all related articles

Related Experiment Video

Updated: May 13, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

[Bacteremia and sepsis].

S Hagel1, M W Pletz, F M Brunkhorst

  • 1Zentrum für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena, Erlanger Allee 101, 07740 Jena. stefan.hagel@med.uni-jena.de

Der Internist
|March 13, 2013
PubMed
Summary
This summary is machine-generated.

Bacteremia, the presence of bacteria in the blood, and sepsis, a clinical diagnosis, are increasing across Europe. Understanding their distinct definitions is crucial for interpreting medical literature and patient outcomes.

More Related Videos

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

Related Experiment Videos

Last Updated: May 13, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

Area of Science:

  • Clinical microbiology
  • Infectious diseases
  • Epidemiology

Context:

  • Bacteremia and sepsis are prevalent clinical issues.
  • Definitions and terminology vary among clinicians, epidemiologists, and microbiologists.
  • A pan-European increase in bacteremia rates (Gram-negative and Gram-positive) is observed.

Purpose:

  • To clarify the distinctions between bacteremia and sepsis.
  • To highlight recent trends in bacteremia and sepsis.
  • To review current diagnostic and therapeutic approaches.

Summary:

  • Bacteremia is a microbiological finding (bacteria in blood), while sepsis is a clinical diagnosis requiring further specification.
  • Increasing patient age and the rise of invasive diagnostics/therapies contribute to higher bacteremia rates.
  • Healthcare-associated infections are a significant factor in bacteremic infections.

Impact:

  • Improved understanding of bacteremia and sepsis terminology enhances literature interpretation.
  • Awareness of increasing rates and contributing factors aids in public health strategies.
  • Knowledge of recent diagnostic and therapeutic advancements supports clinical decision-making.