Related Experiment Video
Updated: May 13, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Caustic ingestion: a possible cause of eosinophilic esophagitis?
Matjaž Homan1, Rok Orel, Chris Liacouras
1University Children's Hospital, Bohoričeva 20, 1000 Ljubljana, Slovenia. matjaz.homan@guest.arnes.si
Abstract:
Eosinophilic esophagitis (EoE) is an emerging disease in both pediatric and adult patients. It is a chronic disease of the esophagus and refers to intense eosinophilic infiltration limited to the esophageal epithelium in the absence of gastroesophageal reflux disease. In most patients, EoE is thought to be part of an allergic response to food antigens or aeroallergens. One such trigger could be caustic damage of the mucosa. To the best of our knowledge, the following case report describes for the first time the possible association between caustic injury of the esophagus and EoE.
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