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Published on: March 14, 2019
Osteomyelitis and beyond
1E. B. Singleton Department of Pediatric Radiology, Texas Children's Hospital, 6701 Fannin St., Ste. 470, Houston, TX 77030, USA. rpguille@texaschildrens.org
Abstract:
Musculoskeletal infections are a cause of considerable morbidity in children. Symptoms and signs are often nonspecific, and imaging is needed to define the anatomical location of infected tissue or fluid collections for diagnostic aspiration or biopsy. Prompt diagnosis and precise localization of the infection site has become even more imperative with the emergence and dissemination of highly invasive organisms such as community-acquired Staphylococcus aureus. Although radiography, bone scintigraphy and US continue to play a role, MRI is now the preferred imaging modality for definitive evaluation of pediatric musculoskeletal infections because of its capability of simultaneously assessing the osseous, articular and muscular structures without ionizing radiation exposure. This article focuses on the imaging characteristics of osteomyelitis, septic arthritis and pyomyositis and the differentiating features of potential mimics of infection.
Insights
Pediatric musculoskeletal infections require prompt diagnosis. Magnetic resonance imaging (MRI) is the preferred method for precisely locating infections like osteomyelitis and septic arthritis without radiation.
Area of Science:
- Pediatric Radiology
- Musculoskeletal Imaging
- Infectious Diseases
Background:
- Musculoskeletal infections in children cause significant morbidity.
- Nonspecific symptoms necessitate advanced imaging for diagnosis and localization.
- Emergence of invasive pathogens like community-acquired Staphylococcus aureus heightens the need for accurate diagnostics.
Purpose of the Study:
- To review the imaging characteristics of pediatric musculoskeletal infections.
- To highlight the role of MRI in definitive evaluation.
- To differentiate infections from mimics.
Main Methods:
- Review of imaging modalities including radiography, bone scintigraphy, ultrasound (US), and magnetic resonance imaging (MRI).
- Focus on MRI's capabilities in assessing osseous, articular, and muscular structures.
- Discussion of imaging features for osteomyelitis, septic arthritis, and pyomyositis.
Main Results:
- MRI is the preferred modality for definitive evaluation of pediatric musculoskeletal infections.
- MRI offers comprehensive assessment without ionizing radiation.
- Imaging characteristics of specific infections and their mimics are detailed.
Conclusions:
- Prompt and precise localization of pediatric musculoskeletal infections is crucial.
- MRI provides superior diagnostic value for these conditions.
- Understanding imaging features aids in differentiating true infections from other pathologies.
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