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Rare Event Detection Using Error-corrected DNA and RNA Sequencing
10:36

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

RNA interference and deep sequencing as tools for identifying new genes involved in leukemogenesis

T D Lebedev1, P V Spirin, N N Orlova

  • 1Russian Academy of Sciences, Moscow, Russia.

Doklady. Biochemistry and Biophysics
|March 13, 2013
PubMed
Abstract

No abstract available in PubMed .

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Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...