CASP-9 gene functional polymorphisms and cancer risk: a large-scale association study plus meta-analysis

Z Y Zhang1, Y Xuan, X Y Jin

  • 1Department of Medical Oncology, Shengjing Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.

Summary

Genetic variations in CASP-9 influence cancer risk. The rs4645981 T allele may increase neoplasm susceptibility, while rs1052576 A and rs2308941 T alleles appear protective against cancer.

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