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Multiple periodontal abscesses after systemic antibiotic therapy
H H Topoll1, D E Lange, R F Müller
1Department of Periodontology, School of Dentistry, Westälische Wilhelms-Universität Münster, FRG.
Journal of Clinical Periodontology
|April 1, 1990
Summary
Systemic antibiotics may trigger multiple periodontal abscesses in patients with advanced periodontal disease. This occurs by altering oral microbiota, leading to antibiotic-resistant bacterial strains and abscess formation.
Area of Science:
- Periodontology
- Microbiology
Background:
- Multiple periodontal abscesses can occur in medically compromised individuals.
- Patients with advanced periodontal disease are susceptible to recurrent infections.
Purpose of the Study:
- To investigate the role of prior antibiotic use in the development of multiple periodontal abscesses.
- To identify the microbial composition of periodontal abscesses in patients with advanced periodontal disease.
Main Methods:
- Examination of patients with multiple periodontal abscesses and no significant medical history.
- Analysis of subgingival plaque samples from abscess sites.
- Identification of anaerobic microbiota and assessment of antibiotic resistance patterns.
Main Results:
- Patients had advanced periodontal disease with significant probing depths and attachment loss.
- Prevalent anaerobic bacteria included Bacteroides gingivalis, Fusobacterium nucleatum, and Streptococcus intermedius.
- Antibiotic-resistant bacterial strains were found in 55% of samples.
Conclusions:
- Systemic antibiotic therapy without concurrent subgingival debridement can alter subgingival microbiota.
- This alteration may promote the development of multiple periodontal abscesses in patients with advanced periodontal disease.