Related Experiment Videos
The effect of platelet releasate on wound healing in animal models
G A Ksander1, S J Sawamura, Y Ogawa
1Celtrix Laboratories, Collagen Corporation, Palo Alto, CA 94303.
Journal of the American Academy of Dermatology
|May 1, 1990
Abstract:
The alpha granules of platelets contain growth factors that are important in wound healing. We found that a major effect of thrombin-induced human platelet releasates in animal models of wound healing is to enhance the development of granulation tissue and new connective tissue matrix. These studies provide further evidence that platelet-derived protein factors may be useful in treating full-thickness dermal wounds by increasing the rate of granulation tissue formation.