Related Experiment Video
Updated: May 13, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
Computational phlebology: reviewing computer models of the venous system
1Radiation Inspection and Control Service, Department of Labour Inspection, Ministry of Labour and Social Insurance, Nicosia, Cyprus. C.Zervides@euc.ac.cy
Computational modeling of the venous system is crucial for understanding deep vein thrombosis. This review highlights physiological conditions and summarizes existing models, aiding future cardiovascular engineering research.
Area of Science:
- Cardiovascular Engineering
- Biomedical Engineering
- Hemodynamics
Background:
- Limited focus on venous system and valves in cardiovascular engineering.
- Venous valve hemodynamics are implicated in deep vein thrombosis development.
- Need for enhanced collaboration between clinicians and engineers.
Purpose of the Study:
- Provide physiological conditions for computational venous system models.
- Summarize existing computational models of the venous system.
- Explore limitations and application ranges of current models.
Main Methods:
- MEDLINE literature search from 1940 to present.
- Review and categorization of published computational models.
- Analysis of model complexity, laws, and physiological considerations.
Main Results:
- Diverse computational models exist, varying in complexity and application.
- Lumped parameter models offer boundary conditions for 1D/3D models.
- 1D and 3D models incorporate analytical equations and hemodynamic principles, including venous compliance and valve effects.
Conclusions:
- Computer modeling significantly advances understanding of venous physiology.
- Modeling facilitates evaluation of venous system hemodynamic interactions.
- Future research should integrate detailed physiological conditions into advanced models.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Varicose Veins I: Introduction
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Venous Thrombosis III: Interprofessional Care
