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Updated: May 13, 2026

An In Vitro Approach to Study Mitochondrial Dysfunction: A Cybrid Model
Published on: March 9, 2022
Management of patients with dental disease and mitochondrial disorders
Adam A Shakir1, Doug M Turnbull, James R Adams
1Department of Oral and Maxillofacial Surgery, Newcastle General Hospital, UK.
Unlabelled:
This case report describes dental disease associated with mitochondrial disease (Leigh's disease) in a young adult. Normal preventive dentistry is difficult in these groups of patients and often leads to management required in secondary care. An awareness of the background pathology is needed when managing these groups of patients. Management of dental pathology in this particular patient often required input from other specialties to ensure a successful outcome.
Clinical Relevance:
To raise awareness of the dental pathologies patients with mitochondrial disease may experience as they present to the general dental practitioner, and what treatments may be appropriate.
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