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Updated: May 13, 2026

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy
Published on: January 25, 2019
Cytomegalovirus retinitis in a patient with proliferative diabetes retinopathy
Purpose:
To report a case of cytomegalovirus (CMV) retinitis in an immunocompetent patient with proliferative diabetic retinopathy (PDR).
Design:
Case report.
Methods:
A 69-year-old man presented with a 44-year history of diabetes mellitus and 4 years of PDR. Fundus of left eye could not be visualized because of vitreous hemorrhage. Laboratory tests indicated normal immunological status.
Results:
Yellowish white retinal exudative lesion and whitening inside vascular arcades were observed during vitrectomy. Multiplex PCR using vitreous sample detected CMV DNA at 4.37 × 10(4) copies/mL. CMV retinitis was diagnosed.
Conclusions:
If atypical findings of PDR are observed, a multiplex PCR test should be performed for further investigation.
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