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Updated: May 13, 2026

A Murine Tail Lymphedema Model
Published on: February 10, 2021
Generalized lymphatic malformation with chylothorax: long-term management of a highly morbid condition in a pediatric
Wendy Chen1, Denise Adams, Manish Patel
1Department of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Abstract:
Generalized lymphatic malformation (GLM) often causes chylothorax, which can be a highly morbid condition. Chylothorax in a pediatric patient with a lymphangiogenic disorder may be especially resistant to therapy, requiring more aggressive measures. We discuss the complex ongoing long-term management of a pediatric patient with GLM who presented with massive, persistent left chylothorax, which resolved by surgical ligation of the thoracic duct and medical management.
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