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Related Experiment Videos

[Intravascular hemolysis after prosthetic valve replacement].

T Yuda1, Y Morishita, K Arikawa

  • 1Second Department of Surgery, Faculty of Medicine, Kagoshima University, Japan.

[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
|February 1, 1990
PubMed
Summary

The St. Jude Medical valve showed higher intravascular hemolysis markers than the Björk-Shiley valve in mitral replacements. Close observation is recommended for patients with subclinical hemolysis after mechanical valve surgery.

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Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science

Background:

  • Mechanical heart valves, specifically St. Jude Medical (SJM) and Björk-Shiley (B-S) models, are used in single valve replacements.
  • Intravascular hemolysis is a potential complication following mechanical valve implantation.

Purpose of the Study:

  • To evaluate and compare the incidence of intravascular hemolysis between SJM and B-S mechanical heart valves.
  • To assess the correlation between valve type, position, size, and hemolysis markers.

Main Methods:

  • Retrospective analysis of patients undergoing single valve replacement with either SJM or B-S prostheses.
  • Monitoring of serum lactate dehydrogenase (LDH), indirect bilirubin, GOT, hemoglobin, and reticulocyte counts.
  • Echocardiography to rule out paravalvular leakage.

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Main Results:

  • Patients with SJM mitral valves exhibited significantly higher LDH, GOT, and reticulocyte counts compared to B-S mitral valves.
  • No significant difference in hemolysis markers was observed between SJM and B-S valves in the aortic position.
  • No correlation was found between prosthesis size and hemolysis severity.

Conclusions:

  • The findings suggest a higher propensity for hemolysis with SJM mitral valves compared to B-S valves.
  • Close postoperative monitoring is crucial for patients with subclinical hemolysis after mechanical valve replacement.