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Updated: May 13, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Incomplete Kawasaki disease.

Margarita M Miller¹, Adam H Miller

¹Department of Pediatrics, University of Texas Children's Hospital, Our Children Pediatrics, Carrollton, Dallas, TX 75007, USA.

The American Journal of Emergency Medicine

|March 14, 2013

Summary

This summary is machine-generated.

A child presented with symptoms including rash and peeling skin, consistent with incomplete Kawasaki disease. Early diagnosis and treatment are crucial for managing this inflammatory condition in pediatric patients.

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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

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Published on: September 14, 2010

Establishment and Quantification of De Novo Lytic Infection by Cell-free Kaposi's Sarcoma-Associated Herpesvirus

Establishment and Quantification of De Novo Lytic Infection by Cell-free Kaposi's Sarcoma-Associated Herpesvirus

Published on: August 15, 2025

Area of Science:

Pediatrics
Immunology
Infectious Diseases

Background:

Kawasaki disease is a critical illness in children, characterized by systemic vasculitis.
Incomplete Kawasaki disease presents with fewer than the typical diagnostic criteria, posing diagnostic challenges.

Observation:

A 4-year-old boy exhibited mucocutaneous findings such as lip and oral cavity changes, a generalized rash, and extremity edema.
Desquamation was noted in the periungual, groin, and perianal regions.
The patient's sibling had a recent diagnosis of Kawasaki disease.

Findings:

Laboratory results revealed elevated inflammatory markers: erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP).
Elevated serum gamma-glutamyl transferase (GGT) was also observed.
Diagnosis of incomplete Kawasaki disease was confirmed following consultations with infectious disease and cardiology specialists.

Implications:

This case highlights the importance of considering Kawasaki disease in children with suggestive symptoms, even with atypical presentations.
Prompt recognition and management of incomplete Kawasaki disease are vital to prevent cardiac complications.
Pediatricians and healthcare providers should maintain a high index of suspicion for Kawasaki disease, especially in patients with a relevant exposure history.