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Updated: May 13, 2026

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Sapheon: the solution?

J Lawson1, S Gauw, C van Vlijmen

  • 1Skin and Vein Clinic Oosterwal, Comeniusstraat 3, 1817MS Alkmaar, The Netherlands. jalawson@me.com

Phlebology
|March 14, 2013
PubMed
Summary
This summary is machine-generated.

New tumescentless techniques for varicose vein treatment, like VenaSeal™, offer comparable short-term efficacy to thermal ablation with minimal discomfort. However, some patients experience temporary recovery issues like thrombophlebitis.

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Area of Science:

  • Vascular Surgery
  • Minimally Invasive Procedures

Background:

  • Endovenous techniques are effective alternatives to open surgery for varicose veins, offering less pain and faster recovery.
  • Tumescent anesthesia, while safe, has drawbacks including a steep learning curve and painful administration.

Purpose of the Study:

  • To investigate the efficacy and safety of tumescentless techniques for varicose vein treatment.
  • To compare VenaSeal™ outcomes with existing thermal ablation methods.

Main Methods:

  • Review of short-term and one-year results for VenaSeal™ Sapheon Closure System.
  • Comparison with data from thermal ablation procedures.

Main Results:

  • VenaSeal™ shows comparable short-term results to thermal ablation and is safe with no serious adverse events.
  • Minimal perioperative pain with VenaSeal™, but 14-15% of patients experience thrombophlebitis post-procedure.
  • One-year follow-up in a feasibility study indicates durable closure with VenaSeal™.

Conclusions:

  • Tumescentless VenaSeal™ is a safe and effective option for varicose vein treatment with minimal patient discomfort.
  • Further long-term studies and randomized controlled trials are needed to fully establish its benefits and compare it directly with other methods like ClosureFast™.