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Related Experiment Video

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Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

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Published on: May 31, 2016

Multiple supramassetric dystrophic calcinosis.

Syed Ahmed Mohiuddin¹, Sheeraz Badal, Amol Doiphode

¹Department of Oral and Maxillofacial Surgery, MIDSR Dental College and Hospital, Latur, Maharashtra, India.

Annals of Maxillofacial Surgery

|March 14, 2013

Summary

Dystrophic calcification involves calcium salt deposition in injured tissues with normal metabolism. This case study details surgical removal of calcified nodules from a young patient's masseter muscle.

Keywords:

Calcium and phosphorous metabolism dystrophic calcification

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Area of Science:

Pathology
Biomineralization
Surgical Oncology

Background:

Dystrophic calcification is characterized by calcium salt deposition in degenerated or injured tissues.
It occurs despite normal serum calcium and phosphorus levels, suggesting localized pathological processes.
The underlying pathophysiology remains incompletely understood, highlighting a need for further research.

Observation:

A 17-year-old male presented with dystrophic calcifications affecting the right masseter muscle.
The calcifications manifested as palpable nodules within the muscle tissue.
Clinical presentation suggested a localized degenerative or reactive process.

Findings:

Surgical excision of the calcified nodules was successfully performed using an intraoral surgical approach.
Histopathological examination confirmed the presence of dystrophic calcification within the excised tissue.
The patient's systemic calcium and phosphorus metabolism was within normal limits.

Implications:

This case underscores the importance of considering dystrophic calcification in the differential diagnosis of masseteric masses, even in young individuals.
Surgical intervention can be effective for symptomatic or problematic calcifications.
Further investigation into the specific triggers and mechanisms of dystrophic calcification in soft tissues is warranted.