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Updated: May 13, 2026
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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Prostate cancer detection at repeat biopsy: can pelvic phased-array multiparametric MRI replace saturation biopsy?
Pietro Pepe1, Antonio Garufi, Giandomenico Priolo
1Urology Unit, Cannizzaro Hospital, via Messina 829, Catania, Italy. piepepe@hotmail.com
Anticancer Research
|March 14, 2013
Summary
Multiparametric MRI enhances prostate cancer (PCa) detection accuracy during saturation prostate biopsy (SPBx). Suspicious lesions over 10 mm on MRI are highly predictive of PCa, improving anterior zone diagnosis.
Area of Science:
- Urology
- Radiology
- Oncology
Background:
- Prostate cancer (PCa) diagnosis often relies on prostate biopsy.
- Saturation prostate biopsy (SPBx) is used for repeat sampling.
- Accuracy of MRI in guiding biopsy requires further evaluation.
Purpose of the Study:
- To evaluate the accuracy of magnetic resonance imaging (MRI) in diagnosing prostate cancer (PCa).
- To assess MRI's role in guiding saturation prostate biopsy (SPBx).
Main Methods:
- 78 patients underwent repeat SPBx with a median of 28 cores.
- Multiparametric MRI (3 Tesla) was performed before SPBx.
- Suspicious lesions identified by MRI were targeted for additional biopsies.
Main Results:
- PCa was diagnosed in 32 (41%) cases.
- SPBx diagnosed 87.5% of PCa, while MRI-targeted biopsy diagnosed 81.2%.
- MRI improved detection of anterior zone cancers and correlated lesion size with diagnosis and Gleason score.
Conclusions:
- Multiparametric MRI enhances SPBx accuracy, particularly for anterior zone PCa.
- MRI-identified lesions >10 mm are highly predictive of PCa (approx. 70% accuracy).
