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Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...

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Related Experiment Video

Updated: May 13, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

[Is psoriasis a dependent cardiovascular risk factor?].

Marlies Wakkee1, Elke M G J de Jong

  • 1Erasmus MC, afd. Dermatologie, Rotterdam, the Netherlands.

Nederlands Tijdschrift Voor Geneeskunde
|March 15, 2013
PubMed
Summary
This summary is machine-generated.

Psoriasis, a chronic inflammatory skin disease, may increase cardiovascular risk. However, current evidence is insufficient to prove a direct link, necessitating further research before changing patient care.

Related Experiment Videos

Last Updated: May 13, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Dermatology
  • Cardiology
  • Epidemiology

Context:

  • Psoriasis affects 2% of the Dutch population as a chronic inflammatory skin condition.
  • A hypothesis suggests psoriasis-related chronic inflammation increases cardiovascular risk.
  • Observational studies show an association, but confounding factors exist.

Purpose:

  • To evaluate the evidence linking psoriasis to increased cardiovascular risk.
  • To determine if psoriasis independently contributes to cardiovascular disease.
  • To assess the need for altered cardiovascular screening in psoriasis patients.

Summary:

  • Current evidence is insufficient to establish a direct, independent link between psoriasis and cardiovascular risk.
  • Observed associations may be influenced by lifestyle factors, medication, psoriatic arthritis, or detection bias.
  • More rigorous studies, such as cohort studies or randomized controlled trials, are required.

Impact:

  • Current evidence does not support changing cardiovascular screening or care protocols for psoriasis patients.
  • Further research is needed to clarify the independent role of psoriasis in cardiovascular risk.
  • Findings highlight the complexity of managing comorbidities in chronic inflammatory diseases.