[A woman with a linear skin eruption]

Area of Science:

• Dermatology
• Toxicology
• Integrative Medicine

Background:

• Immune-boosting supplements are widely used for general health.
• Shiitake mushrooms (Lentinula edodes) are a common ingredient in such supplements.
• Cutaneous reactions to ingested substances are a known clinical concern.

Observation:

• A 31-year-old woman presented with pruritic, linear skin lesions.
• The lesions appeared on her trunk and right upper leg.
• The onset of symptoms followed the ingestion of three tablets of an immune-boosting supplement containing shiitake mushrooms.

Findings:

• The clinical presentation and patient history were characteristic of shiitake dermatitis.
• This diagnosis was established based on the distinct morphology and distribution of the rash.
• The temporal relationship between supplement intake and lesion development was a key diagnostic factor.

Implications:

• Shiitake dermatitis is a potential adverse reaction to consuming shiitake mushrooms.
• Dermatologists and healthcare providers should consider shiitake dermatitis in patients with similar presentations.
• Awareness of this reaction is important for patients using mushroom-based supplements.