Related Experiment Video
Updated: May 13, 2026

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells
Published on: October 10, 2017
Is there a role for curcumin in the treatment of bipolar disorder?
Elisa Brietzke1, Rodrigo B Mansur, Andre Zugman
1Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Abstract:
Curcumin is a polyphenolic nonflavonoid compound extracted from the rhizome of turmeric (Curcuma longa), a plant commonly used in Indian and Chinese traditional medicine to treat rheumatism, cough, inflammation and wounds. Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. These targets include, but are not limited to, transcription factors activated by environmental stressors and pro-inflammatory cytokines, protein kinases (PKA, PKC), enzymes, growth factors, inflammatory mediators, and anti-apoptotic proteins (Bcl-XL). Herein, we review previous studies on the anti-inflammatory and anti-oxidant properties of curcumin and discuss its therapeutic potential in BD.
More Related Videos
Related Concept Videos
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Antidepressant Drugs: MAOIs and Other Agents
Drug Therapy
Antianxiety Medications
Psychosis: Goals of Pharmacotherapy
Depression: Overview
