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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Deep-vein thrombosis and septic pulmonary emboli in methicillin-sensitive Staphylococcus aureus infection

Banani Poddar1, Jyoti Narayan Sahoo, Mohan Gurjar

  • 1Department of Critical Care Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. bananip@sgpgi.ac.in

Paediatrics and International Child Health
|March 15, 2013
PubMed

Insights

Deep-vein thrombosis (DVT) in children is often linked to underlying causes. This study describes cases of DVT in previously healthy children with Staphylococcus aureus sepsis, specifically the methicillin-sensitive type.

Area of Science:

  • Pediatric Infectious Diseases
  • Hematology

Background:

  • Deep-vein thrombosis (DVT) in pediatric populations is frequently associated with identifiable predisposing factors.
  • Staphylococcal sepsis, particularly with methicillin-resistant strains (MRSA), is a known risk factor for DVT and septic pulmonary emboli.

Observation:

  • This study details the clinical presentation of four previously healthy children.
  • These children developed community-acquired sepsis caused by methicillin-sensitive Staphylococcus aureus (MSSA).
  • All four children also experienced deep-vein thrombosis.

Findings:

  • The cases highlight a clinical association between MSSA sepsis and DVT in pediatric patients.
  • This contrasts with the more commonly reported association between MRSA and DVT in similar contexts.
  • The clinical features observed in these four children provide insight into this specific presentation.

Implications:

  • Recognizing DVT as a potential complication of MSSA sepsis in children is crucial for timely diagnosis and treatment.
  • This finding may broaden the understanding of risk factors for pediatric DVT.
  • Further research is warranted to elucidate the mechanisms and frequency of DVT associated with MSSA sepsis in children.

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